131. Cai, NG; Zhan, XZ; Zhang, QY; Di, HN; Chen, C; Hu, YY; Yan, XM*. Red blood cell-derived small extracellular vesicles inhibitlnfluez virus through surface-displayed sialic acids,  Angew. Chem. Int. Ed. 2024, e202413946

130. Cai, NG; Zhan, XZ; Chen, Y; Xue, JW; Chen, C; Li, YR; Tian, Y; Yan, XM. Surface sialic acid detection of small extracellular vesicles at the single-particle level by nano-flow cytometry,Anal. Chem. 2024, 96, 12718-12728

129. Wu, LN;*,‡ Zhang, YZ,‡ Hong, XY; Wu, MK; Wang, LA; Yan, XM*. Deciphering the relationship between cell growth and cell cycle in individual Escherichia coli cells by flow cytometry, Anal. Chem. 2024, 96, 12444-12452

128. Chen, CX*; Pan, XP; Sun, MD; Wang, JL; Su, XQ; Zhang, TY; Chen, YL; Wu, DR; Li, J; Wu, SQ*; Yan, XM*. Phospholipid-anchored ligand conjugation on extracellular vesicles for enhanced cancer targeting, Small 2024, 2310712

127. Su, LY+; Xu, JY+; Chen, L; Gao, KM; Hu, YY; Xue, CF; Yan, XM*. Nano-flow cytometry unveils mitochondrial permeability transition process and multi-pathway cell death induction for cancer therapy, Cell Death Disc. 2024, 10, 176

126.Su, LY; Gao, KM; Tian, Y; Xiao, X; Lu, C; Xu, JY; Yan, XM*, Mitochondrial Esterase Activity Measured at the Single OrganelleLevel by Nano-flow Cytometry, Anal. Chem. 2024, 01, 3c04321.https://doi.org/10.1021/acs.analchem.3c04321

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125. Lozano-Andr´es*, E; Van Den Broeck, T; Wang, LL; Mehrpouyan, M; Tian, Y; Yan, XM; Arkesteijn, G.J.A.; Wauben, M.H.M.. Intrinsic variability of fluorescence calibrators impacts the assignment of MESF or ERF values to nanoparticles and extracellular vesicles by flow cytometry.Nanomed.-Nanotechnol. 2024, 56, 102720

124. Welsh, J.A.; Goberdhan, D.C.I.; O’Driscoll, L., Théry, T.; Witwer, K.W…. YAN, XM… Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches, J. Extracell. Vesicles 2024, 13, e12404

123.Chen, C; Cai, NG; Niu, Q; Tian, Y; Hu, YY; Yan, XM*, Quantitative assessment of lipophilic membrane dye-basedlabelling of extracellular vesicles by nano-flow cytometry, J. Extracell. Vesicles. 2023‍, 12, e12351.

122. Chen, CX; Chen, C; Li, YR; Gu, RL; Yan, XM*, Characterization of lipid-based nanomedicines at the single-particle level, Fundamental Res. 2023, 3, 488-504

121. Li, LH#; Wang, S#; Xue, JW; Lin, Y; Su, LY; Xue, CF; Mao, CP; Cai, NG; Tian, Y; Zhu, SB; Wu, LN; Yan, XM*, Development of Spectral Nano-Flow Cytometry for High-Throughput Multiparameter Analysis of Individual Biological Nanoparticles. Anal. Chem., 2023, 95, 6, 3423-3433.

120.Chen, C; Li, YR; Wang, QQ; Cai, NG; Wu, LN;Yan, XM*,Single-particle assessment of six different drug loading strategies for incorporating doxorubicin into small extracellular vesicles, Anal. Bioanal. Chem. 2023, 415, 1287–1298

119. 陈晨, 陈妍, 薛钧炜, 蔡年桂, 颜晓梅*, 细胞外囊泡与脂质体融合的单颗粒水平表征, 《分析化学》,2023, 51, 1283-1291

118. 薛乘风,王文婷,毛翠萍,吴丽娜,颜晓梅*,纳米流式检测技术用于益生菌产品的细菌活性及上消化道耐受性分析, 《分析化学》,2023, 51, 502-512

117. Xue, TW; Peng, L.;* Syzgantseva, O.A.; Syzgantseva, M.A.; Guo, PW; Lai, HY; Li, RQ; Chen, JW; Li, SM;  Yan, XM; Yang, SL;* Li, J;* Han, BX; Queen, W.L.* Rapid, Selective Extraction of Silver from Complex Water Matrices with a Metal-Organic Framework/Oligomer Composite Constructed via Supercritical CO2, Angew. Chem. Int. Ed. 2023, 62, e202309737.

116. Welsh*, J.A.; Arkesteijn, G.J.A.; Bremer, M.; Cimorelli, M.; Dignat-George, F.; Giebelc, B.; Görgensi, A.; Hendrix, A.; Kuiper, M.; Lacroix, R.; Lannigan, J.; van Leeuwen, T.G.; Lozano-Andrés, E.; Rao, S.; Robert, S.; dRond, L.; Tang, V.A.; Tertel, T.; Yan, XM; Wauben, M.H.M.*, Nolan. J.P.;*, Jones, J.C.;*, Nieuwland, R.;* van der Pol, E.;*. A compendium of single extracellular vesicle flow cytometry, J. Extracell. Vesicles 2023, 12, e12299.

115. Zhang, MR+; Xu, F+; Liu, WJ; Hou, YQ; Su, LY; Zhang, X; Zhang, RH; Zhou, LJ; Yan, XM;Wang, M*; Hou, X*; Cao, Y*. Antibacterial evaporator based on reduced graphene oxide/polypyrrole aerogel for solar-driven desalination, Nano Res. 2023, 16, 4219–4224.

114. Li, Q;# Li, B;# Ye, T; Xu, WR; Yin, H; Deng, ZF; Li, HY; Yan, XM; Hao, XK; Li, L; Tao, ZH; Liu, BC; Chen, ZS; Luo, L; Qian, H*; Fu, QL*; Wang, Q*; Zheng, L*; Wang, Y*. Requirements for human mesenchymal stem cell derived small extracellular vesicles, Interdiscip. Med. 2023, 1, e20220015.

113. Gao, KM#; Lian, H#; Xue, CF; Zhou, J; Yan, XM*, High-Throughput Counting and Sizing of Therapeutic Protein Aggreates in the Nanometer Size Range by Nano-Flow Cytometry. Anal. Chem., 2022, 94, 50, 17634-17644.




112. Chen, CX; Zhou, YX; Chen, C;  Zhu, SB; Yan, XM*, Quantification of Available Ligand Density on the Surface of Targeted Liposomal Nanomedicines at the Single-Particle Level. ACS Nano, 2022, 16, 6886-6897.


111. Liu, HS; Tian, Y;  Xue CF; Niu, Q; Chen, C;Yan, XM*. Analysis of extracelluar vesicle DNA at the single-vesicle level by nano-flow cytometry. J. Extracell. Vesicles, 2022, 11, e12206.

110. Tian, Y#; Xue, CF#; Zhang, WQ; Chen, CX; Ma, L; Wu, LN; Yan, XM*, Refractive Index Determination of Individual Viruses and Small Extracellular Vesicles in Aqueous Media Using Nano-Flow Cytometry. Anal. Chem., 2022, 94, 41, 14299-14307.



109. Hu, YY; Tian, Y; Di, HN; Xue, CF; Zheng, YP; Hu, B*; Lin, Q*; Yan, XM*. Noninvasive diagnosis of nasopharyngeal carcinoma based on phenotypic profiling of viral and tumor markers on plasma extracellular vesicles, Anal. Chem. 2022, 94, 9740−9749.

108. Liu, HS; Yuan WL; Pang QS; Xue CF; Yan, XM*. Single-particle analysis of tear fluid reveals abundant presence of tissue factor-exposing extracellular vesicles with strong coagulation activity. Talanta, 2022, 239, 123089.

107. Wu, YF; Ying, SW; Su, LY; Du, JJ; Zhang, L; Chen, BW; Tian, HR; Xu, H; Zhang, ML; Yan, XM; Zhang, QY*; Xie, SY; Zheng, LS. Nitrogen-embedded quintuple [7]helicene: A helicene-azacorannulene hybrid with srtong near-infrared fluorescence, J. Am. Chem. Soc. 2022, 144, 10736-10742.

106. Kou, M+; Huang, L+; Yang, JJ; Chiang, ZX; Chen,SX; Liu, J; Guo, LY; Zhang, XX; Zhou, XY; Xu, X; Yan, XM; Wang, Y; Zhang, JQ; Xu, AM; Tse, HF; Lian, QZ*. Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool? Cell Death & Disease, 2022, 13, 580.

105. Niu, Q#; Ma, L#; Zhu, SB; Li, L; Zheng, QS; Hou, JB; Lian, H; Wu, LN; Yan, XM*. Quantitative assessment of the physical virus titer and purity by ultrasensitive flow virometry, Angew. Chem. Int. Ed., 2021, 60, 9351-9356.


104. Gao, KM#; Zhou, YX#; Liu, QY; Lu, JY; Su, LY; Su, R; Zhang, MM; Tian, Y; Wu, LN; Yan, XM*. High-Throughput Human Telomere Length Analysis at the Single-Chromosome level by FISH Coupled with Nano-Flow Cytometry, Anal. Chem., 2021, 93, 9531-9540.


103. Wu, LN*; Su, LQ#; Deng, MF#; Hong,  XY; Wu, MK; Zhang, MM; Bouveret, E; Yan, XM*. Dual-fluorescent bacterial two-hybrid system for quantitative protein-protein interaction measurement via flow cytometry. Talanta, 2021, 233, 122549.

102. Wu, LN*; Hong, XY; Luan, T; Zhang, YZ; Li, LH; Huang, TX; Yan, XM*. Multiplexed detection of bacterial pathogens based on a cocktail of dual-modified phages. Anal. Chim. Acta, 2021, 1166, 338596.

101. Xu, JY; Su, LY; Han, JY; Gao, KM; Zhang, MM; Wang, S; Chen, CX; Yan, XM*. Rapid and quantitative in vitro analysis of mitochondrial fusion and its interplay with apoptosis. Talanta, 2021, 222, 121523.

100. 牛倩;田野;吴明凯;张宇豪;陈晨;颜晓梅*. 细菌囊泡纯度、浓度及粒径分布的单颗粒水平定量表征. 分析化学, 2021, 49, 733-742.

99. Chen, CX*; Sun, MD; Wang JL; Su, Ly; Lin, JJ; Yan, XM*; Active cargo loading into extracellular vesicles: Highlights the heterogeneous encapsulation behavior, J. Extracell. Vesicles. 2021, 10, e12163.

98. Chen, CX*; Sun, MD; Liu, X; Wu, WJ; Su, LY; Li, YM; Liu, G*; Yan XM*, Nanoscale, 2021, 13, 3061.

97. Luo, XJ#; Gong, XQ#; Su, LY#; Lin, HY#; Yang, ZX; Yan, XM; Gao, JH*. Activetable Mitochondria-Targeting Organoarsenic Prodrugs for Bioenergetic Cancer Therapy, Angew. Chem. Int. Ed. 2021, 60, 1403-1410.

96. van der Pol. E*; van Leeuwen, R.G.; Yan, XM; Misinterpretation of solid sphere equivalent refractive index measurements and smallest detectable diameters of extracellular vesicles by flow cytometry., Sci. Rep. 2021, 11, 24151.

95. Tian, Y#; Gong, MF#; Hu,YY; Liu, HS; Zhang, WQ; Zhang, MM; Hu, XX; Aubert, D; Zhu, SB; Wu, LN; Yan, XM*. Quality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry. J. Extracell. Vesicles, 2020, 9, 1697028.


94. He, SB; Hong, XY; Zhang, MM; Wu, LN; Yan, XM*. Label-free detection of bacteria in fruit juice by nano-flow cytometry. Anal. Chem., 2020, 92, 2393-2400.



93. Mao, CP; Xue, CF; Wang, XZ; He, SB; Wu, LN; Yan, XM*. Rapid quantification of pathogenic Salmonella Typhimurium and total bacteria in eggs by nano-flow cytometry. Talanta, 2020, 217, 121020.

92. 毛翠萍;林垚;牛倩;薛乘风;颜晓梅*. 高灵敏、宽动态范围纳米流式检测装置的研制及应用. 分析化学, 2020, 48, 838-846.

91. 刘海生;袁文理;陈永钰;陈晨;田野;颜晓梅*. 尿液细胞外囊泡的单颗粒水平多参数定量表征. 分析化学, 2020, 48, 1305-1314.

90. Meng, YF; Cheng, XL; Wang, TT; Hang, W*; Li, XP; Nie, W; Liu, R; Lin, Z; Hang, L; Yin, ZB; Zhang, BL; Yan, XM, Micro-Lensed Fiber Laser Desorption Mass Spectrometry Imaging Reveals Subcellular Distribution of Drugs within Single Cells, Angew. Chem. Int. Ed. 2020, 59, 17864-17871.

89. Welsh, J.A.; Van Der Pol, E.; Arkesteijn, G. J. A.; Bremer, M.; Brisson, A.; Coumans, F.; Dignat-George, F.; Duggan, E.; Ghiran, I.; Giebel, B.; Görgens, A.; Hendrix, A.; Lacroix, R.; Lannigan, J.; Libregts, S.F.W.M; Lozano-Andrés, E.; Morales-Kastresana, A.; Robert, S.; De Rond, L.; Tertel, T.; Tigges, J.; De Wever, O.; Yan, XM; Nieuwland, R.*; Wauben, M.H.M.*; Nolan, J.P.*; Jones, J.C.* MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments, J. Extracell. Vesicles 2020, 9, 1713526.

88. Soekmadji, C.*; Li, B; Huang, YY; Wang, HF; An, TX; Liu, CC; Pan, WL; Chen, J.; Cheung, L.; Manuel Falcon-Perez, J.; Gho, YS; Holthofer, H.B.; Le, M.T.N.; Marcilla, A.; O’Driscoll, L.; Shekari, F.; Shen, TL; Torrecilhas, A.C.; Yan, XM; Yang, FQ; Yin, H; Xiao, Y; Zhao, ZZ; Zou, X; Wang, Q*; Zheng, L*, The future of Extracellular Vesicles as Theranostics - an ISEV meeting report, J. Extracell. Vesicles, 2020, 9, 1809766.

87. Lian, H1; He, SB1; Chen, CX; Yan, XM*, Flow Cytometric Analysis of Nanoscale Biological Particles and Organelles, Annu. Rev. Anal. Chem., 2019, 12, 389-409.



86. Wu, LN*; Zhang, MM; Song, YY; Deng, MF; He, SB; Su, LQ; Chen, Y; Wood, TK; Yan, XM*. Deciphering the Antitoxin-Regulated Bacterial Stress Response via Single-Cell Analysis. ACS Chem. Biol., 2019, 14, 2859-2866.

85. Gao, M1; Lian, H1; Yu, LG; Gong, MF; Ma, L; Zhou, YX; Yu, MX; Yan, XM*, Rolling circle amplification integrated with suspension bead array for ultrasensitive multiplex immunodetection of tumor markers, Anal. Chim. Acta, 2019, 1048, 75-84.

84. Chen, CX*; Gao, KM; Lian, H; Chen, C; Yan, XM*, Single-particle characterization of theranostic liposomes with stimulus sensing and controlled drug release properties, Biosens. Bioelectron. 2019, 131, 185-192.



83. Yin, ZB; Cheng, XL; Liu, R; Li, XP; Hang, L; Hang, W*; Xu, JY; Yan, XM*; Li, JF*; Tian, ZQ; Chemical and Topographical Single-Cell Imaging by Near-Field Desorption Mass Spectrometry, Angew. Chem. Int. Ed., 2019, 58, 4541-4546.

82. Tian, Y; Ma, L; Gong, MF; Su, GQ*; Zhu, SB, Zhang, WQ; Wang, S; Li, ZB; Chen, CX; Li, LH; Wu, LN; Yan, XM*, Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry, ACS Nano, 2018, 12, 671-680.


81. Zhang, WQ; Tian, Y; Hu, XX; He, SB; Niu, Q; Chen, CX; Zhu, SB; Yan, XM*, Light-Scattering Sizing of Single Submicron Particles by High-Sensitivity Flow Cytometry, Anal. Chem. 2018, 90, 12768-12775.




80. 高恺旻, 颜晓梅*. 生物制药领域蛋白质团聚检测技术的研究进展,《分析化学》, 2018, 46(10), 1507-1517.

79. Thery, C; et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines, J. Extracell. Vesicles, 2018, 7, 1535750.

78. Wang, S; Li, LH; Jin, SH; Li, WF; Hang, W; Yan, XM*, Rapid and Quantitative Measurement of Single Quantum Dots in a Sheath Flow Cuvette, Anal. Chem. 2017, 89, 9857-9863.


77. Wu, LN1; Wang, X1; Zhang, JQ; Luan, T; Bouveret, E; Yan, XM*. Flow cytometric single-cell analysis enables quantitative in vivo detection of protein-protein interactions via relative reporter protein expression measurement. Anal. Chem. 2017, 89, 2782-2789.


76. Chen, CX; Zhu, SB; Wang, S; Zhang, WQ; Cheng, Y; Yan, XM*. Multiparameter Quantification of Liposomal Nanomedicines at the Single-particle Level by High Sensitivity Flow Cytometry, ACS Appl. Mater. Interfaces, 2017, 9, 13913-13919.



75. Yan, Y; Meng, LY; Zhang, WQ; Zheng, Y; Wang, S; Ren, B; Yang, ZL*; Yan, XM*. High-Throughput Single-Particle Analysis of Metal-Enhanced Fluorescence in Free Solution Using Ag@SiO2 Core-Shell Nanoparticles, ACS Sensors, 2017, 2017, 2, 1369-1376.




74. He, SB; Hong, XY, Huang, TX; Zhang, WQ; Zhou, YX; Wu, LN; Yan, XM*. Rapid quantification of live/dead lactic acid bacteria in probiotic products using high-sensitivity flow cytometry, Methods Appl. Fluoresc. 2017, 5, 024002.

73. Wang, PY; Zeng, WJ; Liu, J; Wu, YL; Ma, YH; Zeng, ZP; Pang, JY; Zhang, XK; Yan, XM; Sze Tsai Wong, A; Zeng, JZ*. TRC4, an improved triptolide derivative, specifically targets to truncated form of retinoid X receptor-alpha in cancer cells. Biochem. Pharmacol 2017, 124, 19-28.

72. Ma, L1; Zhu, SB1; Tian, Y; Zhang, WQ; Wang, S; Chen, CX; Wu, LN; Yan, XM*. A label-free analysis of single viruses with a resolution comparable to that of electron microscopy and the throughput of flow cytometry, Angew. Chem. Int. Ed., 2016, 55, 10239 –10243. (hot paper)

71. Wu, LN; Song, YY; Luan, T; Ma, L; Su, LQ; Wang S; Yan XM*. Specific detection of live Escherichia coli O157:H7 using tetracysteine-tagged PP01 bacteriophage, Biosens. Bioelectron. 2016, 86, 102-108.


70. Huang, TX1; Zheng, Y1; Yan, Y; Yang, LL; Yao, YH; Zheng, JX; Wu, LN; Wang, X; Chen, YQ; Xing, JC; Yan, XM*. Probing minority population of antibiotic-resistant bacteria, Biosens. Bioelectron. 2016, 80, 323-330. 




69. Wu, LN; Wang, S; Song, YY; Wang, X; Yan, XM*. Applications and challenges for single-bacteria analysis by flow cytometry, Sci. China Chem. 2016, 59, 30-39.

68. Zhu, SB; Chen, CX; Ma, L; Wang, S; Zhang, WQ; Yan, XM*. Development of advanced single-nanoparticle technique for high-resolution nanomedicine characterization, Nanomed-Nanotechnol. 2016, 12, 2, 465-466.

67. Chen, CX; Zhu, SB; Wang, S; Huang, TX; Zhang, WQ; Yan, XM*. Quantitative characterization of doxorubicin-encapsulated liposomes by a laboratory-built high sensitivity flow cytometer, Nanomed-Nanotechnol. 2016, 12, 2, 544-545.

66. 韩锦艳,许静怡,张翔,周颖星,陈超翔,颜晓梅*. 线粒体荧光标记的单颗粒水平高通量评估方法,《分析化学》, 2016, 44, 1171-1177.

65. Zhu, L1; Xiong, P1; Mao, ZY; Wang, YH; Yan, XM; Lu, X; Xu, HC*. Electrocatalytic generation of amidyl radicals for olefin hydroamidation: use of solvent effects to enable anilide oxidation, Angew. Chem. Int. Ed. 2016, 55, 2226-2229. (†, co-first authors)

64. Chen, CX; Zhang, X; Zhang, SY; Zhu, SB; Xu, JY, Zheng, Y; Han, JY, Zeng, JZ; Yan, XM*. Quantification of protein copy number in single mitochondria: the Bcl-2 family proteins, Biosens. Bioelectron. 2015, 74, 476-482.

63. Yu, MX; Wu, LN; Huang, TX; Wang, S; Yan, XM*. Rapid detection and enumeration of total bacteria in drinking water and tea beverages by a laboratory-built high-sensitivity flow cytometer, Anal. Methods. 2015, 7, 3072-3079.

62. 许静怡,陈超翔,韩锦艳,杭纬,颜晓梅*. 线粒体蛋白质组学研究进展,《分析化学》, 2015, 43, 1257-1264.

61. Shen, W; Lin, X; Jiang, CY; Li, CY; Lin, HX; Huang, JT; Wang, S; Liu, GK; Yan, XM; Zhong, QL; Ren, B*, Reliable Quantitative SERS Analysis Facilitated by Core-Shell Nanoparticles with Embedded Internal Standards, Angew. Chem. Int. Ed. 2015, 54, 7308 –7312.

60. Zhang, Z*; Deng, CQ; Meng, LS; Zheng, Y; Yan, XM. A rhodamine hydrazide-based fluorescent probe for sensitive and selective detection of hypochlorous acid and its application in living cells, Anal. Methods. 2015, 7, 107-114.

59. Zhu, SB; Ma, L; Wang, S; Chen, CX; Zhang, WQ; Yang, LL; Hang, W; Nolan, J. P.; Wu, LN; Yan, XM*. Light-scattering detection below the level of single fluorescent molecules for high-resolution characterization of functional nanoparticles. ACS Nano 2014, 8, 10998-11006.


58. Zhang, X; Zhang, SY; Zhu, SB; Chen, S; Han, JY; Gao, KM; Zeng, JZ; Yan, XM*. Rapid identification of mitochondria-targeting anticancer compounds by an in vitro strategy, Anal. Chem. 2014, 86, 5232−5237.


57. Wu, LN; Luan, T; Yang, XT; Wang, S; Zheng, Y; Huang, TX; Zhu, SB; Yan, XM*. Trace detection of specific viable bacteria using tetracysteine-tagged bacteriophages, Anal. Chem. 2014, 86, 907-912.


56. Yang, CW; Chen, S; Zhou, M; Li, Y; Li, YF; Zhang, ZX; Liu, Z; Ba, Q; Li, JQ; Wang, H; Yan, XM*; Ma, DW*; Wang, RX*. Development of 3-Phenyl-N-(2-(3-phenylureido) ethyl)-thiophene-2-sulfonamide compounds as inhibitors of antiapoptotic Bcl-2 family proteins, ChemMedChem, 2014, 9, 1436 - 1452.

55. Xu, F; Zhu, L; Zhu, SB; Yan, XM; Xu, HC*. Electrochemical intramolecular aminooxygenation of unactivated alkenes, Chem. Eur. J. 2014, 20, 12740- 12744.

54. Huang, ZZ; Zhang, SD; Hang, W*; Chen, YD; Zheng, JX; Li, W; Xing, JC; Zhu, EY; Yan, XM. Liquid chromatography-mass spectrometry based serum peptidomic approach for renal clear cell carcinoma diagnosis, J. Pharmaceut. Biomed. Anal. 2014, 100, 175-183.

53. Shao, Q; Zheng, Y; Dong, XM; Tang, K; Yan, XM*; Xing BG*. A covalent reporter of β-lactamase activity for fluorescent imaging and rapid screening of antibiotic-resistant bacteria, Chem. Eur. J., 2013, 19, 10903-10910.

52. Yang, LL1; Huang, TX1; Zhu, SB; Zhou YX; Jiang, YB; Wang, S; Chen, YQ; Wu, LN; Yan XM*. High-throughput single-cell analysis of low copy number β-Galactosidase by a laboratory-built high-sensitivity flow cytometer, Biosens. Bioelectron. 2013, 48, 49-56. 


51. Chen, CX; Zhu, SB; Huang, TX; Wang S; Yan, XM*. Analytical techniques for single-liposome characterization. Anal. Methods, 2013, 5, 2150-2157.

50. Yang, L; Wu, SQ; Lin, BJ; Huang, TX; Chen, XP; Yan, XM; Han, SF*. A targetable nanogenerator of nitric oxide for light-triggered cytotoxicity. J. Mater. Chem. B, 2013, 1, 6115.

49. Huang, ZZ; Chen, YJ; Hang, W.*, Gao, Y.; Lin, L.; Li, D. Y.; Xing, JC; Yan, XM. Holistic Metabonomic Profiling of Urine Affords Potential Early Diagnosis for Bladder and Kidney Cancers, Metabolomics, 2013, 9, 119-129.

48. Zhang, SY1; Zhu, SB1; Yang, LL; Zheng, Y; Gao, M; Wang, S; Zeng, J-Z; and Yan, XM*. High-throughput multiparameter analysis of individual mitochondria, Anal. Chem. 2012, 84, 6421-6428.


47. Yang, LL; Zhou, YX; Zhu, SB; Huang, TX; Wu, LN; Yan, XM*. Detection and quantification of bacterial autofluorescence at the single-cell level by a laboratory-built high-sensitivity flow cytometer, Anal. Chem. 2012, 84, 1526-1532.


46. Huang, H; Chen, ZJ; Yan, XM*. Simultaneous determination of serotonin and creatinine in urine by combining two ultrasound-assisted emulsification microextractions with on-column stacking in capillary electrophoresis. J. Sep. Sci. 2012, 35, 436-444.

45. Lin, L; Huang, ZZ; Gao, Y; Chen, YJ; Hang, W.*, Xing, JC; Yan, XM. LC-MS based serum metabolic profiling for genitourinary cancer classification and cancer type-specific biomarker discovery, Proteomics, 2012, 12, 2238-2246.

44. Lu, N.; Liu, JX; Liu, J.; Zhang, CY; Jiang, FQ; Wu, H.; Chen, LQ; Zeng, WJ; Cao, XH; Yan, TD; Wang, GH; Zhou, H.; Lin, BZ; Yan, XM; Zhang, XK; and Zeng, JZ*. Antagonist effect of triptolide on AKT activation by truncated retinoid X receptor-alpha. PLoS One 2012, 7(4): e35722.

43. Gao, Y.; Yang, N.; Yan, XM; Hang, W.*; Xing, JC; Zheng, J.; Zhu, EY; Huang, BL. Early diagnosis of urinary lithiasis via elementary profile of serum samples, Anal. Methods 2012, 4, 693-698.

42. Wu, LN; Huang, TT; Yang, LL; Pan, JB; Zhu, SB; Yan, XM*. Sensitive and selective bacterial detection using tetracysteine-tagged phages in conjunction with biarsenical dye, Angew. Chem. Int. Ed. 2011, 50, 5873-5877.


41. Zhu, SB; Wang, S; Yang, LL; Huang, TX; Yan, XM*. Progress in the development of techniques based on light scattering for single nanoparticle detection, Sci. China Chem., 2011, 54, 1244-1253.

40. Zheng, Y; Lin, L; Hang, W; Yan, XM*; Marrone, B. L.* Analysis of beryllium to biomolecule binding using a metal specific fluorescent probe and competitive Assay, Talanta, 2011, 85, 638-643.

39. Zhang, Z*; Zheng, Y; Hang, W; Yan, XM*; Zhao, YF. Sensitive and selective off-on rhodamine hydrazide fluorescent chemosensor for hypochlorous acid detection and bioimaging, Talanta, 2011, 85, 779-786.

38. Huang, ZZ; Lin, L; Gao, Y; Chen, YJ; Yan, XM; Xing, JC; Hang, W*. Bladder cancer determination via two urinary metabolites: a biomarker pattern approach, Mol. Cell. Proteomics, 2011, 10, 10.1074/mcp.M111.007922-1–007922-10.

37. Lin, L; Huang, ZZ; Gao, Y; Yan, XM; Xing, JC; Hang, W*. LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery, J. Proteome. Res., 2011, 10, 1396-1405. 

36. Zhu, SB; Yang, LL; Long, Y; Gao, M; Huang, TX; Hang, W; Yan, XM*. Size differentiation and absolute quantification of gold nanoparticles via single particle detection with a laboratory-built high-sensitivity flow Cytometer, J. Am. Chem. Soc. 2010, 132, 12176-12178.


35. Yang, LL; Wu, LN; Zhu, SB; Long, Y; Hang, W; Yan, XM*. Rapid, absolute, and simultaneous quantification of specific pathogenic strain and total bacterial cells using an ultrasensitive dual-color flow Cytometer, Anal. Chem., 2010, 82, 1109-1116.


34. Zhang, ZL; Long, Y; Pan, JB; Yan, XM*. Preparation of fluorescence-encoded microspheres in a core-shell structure for suspension arrays, J. Mater. Chem., 2010, 20, 1179-1185.

33. Long, Y; Zhang, ZL; Yan, XM*; Xing, JC*; Zhang, KY; Huang, JX; Zheng, JX; Li, W. Multiplex immunodetection of tumor markers with a suspension array built upon core-shell structured functional fluorescence-encoded microspheres, Anal. Chim. Acta, 2010, 665, 63-68.

32. Yan, XM; Lin, YM; Huang, RF; Hang, W*; Harrison, W. W. A spectroscopic investigation of the afterglow and recombination process in a microsecond pulsed glow discharge, J. Anal. At. Spectrom., 2010, 25, 534-543.

31. Lin, L; Yu, Q; Yan, XM; Hang, W*; Zheng, JX; Xing, JC; Huang, BL. Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer, Analyst, 2010, 135, 2970-2978.

30. Xing, JC*; Yan, LJ; Zhang, J*; Lin, L; Gao, Y; Chen, WG; Song, XY; Yan, XM; Hang, W*; Huang, BL. A comparative study of elution gradients in UPLC-TOF-MS-based metabonomics research, Chromatographia, 2010, 72, 807-813.

29. Yang, LL; Zhu, SB; Hang, W; Wu, LN; Yan, XM*. Development of an ultrasensitive dual-channel flow cytometer for the individual analysis of nanosized particles and biomolecules, Anal. Chem., 2009, 81, 2555-2563. 28. Ding, J; Lin, L; Hang, W; Yan, XM*. Beryllium uptake and related biological effects studied in THP-1 differentiated macrophages, Metallomics, 2009, 1, 471-478. 

27. Chen, ZJ; Yan, XM*. Simultaneous determination of melamine and 5-hydroxymethylfurfural in milk by capillary electrophoresis with diode array detection, J. Agric. Food Chem., 2009, 57, 8742-8747.

26. Zhang, J*; Yan, LJ; Chen, WG; Lin, L; Song, XY; Yan, XM; Hang, W*; Huang, BL. Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC-oaTOF-MS system, Anal. Chim. Acta, 2009, 650, 16-22. 

25. Chen, LZ; Lin, L; Yu, Q; Yan, XM; Hang, W*; He, J; Huang, BL. Semiquantitative multielemental analysis of biological samples by a laser ionization orthogonal time-of-flight mass spectrometer, J. Am. Soc. Mass Spectrom., 2009, 20, 1355-1358. 

24. Yang, LL; Zhu, SB; Hang, W; Yan, XM*. Development of a single-molecule flow analyzer, Chem. J. Chinese U., 2008, 29, 1549-1551.

23. Zhang, J*; Yan, LJ; Lin, L; Chen, WG; Song, XY; Yan, XM; Hang, W*; Huang, BL. Metabonomics research of diabetic mellitus and diabetic nephropathy based on UPLC-oaTOF-MS system, Chem. J. Chinese U., 2008, 29, 2171-2173.

22. He, J; Zhong, WW; Tang, AJ; Yan, XM; Lewis, C.; Majidi, V.; Hang, W. A fluorescence detection scheme for ultra large molecules after gas phase separation, Talanta, 2007, 71, 2126-2128.

21. Yan, XM*; Zhong, WW; Tang, AJ; Schielke, E. G.; Hang W, Nolan J. P. Multiplexed flow cytometric immunoassay for influenza virus detection and differentiation, Anal. Chem., 2005, 77, 7673-7678.

20. Yan, XM*; Habbersett R. C.; Yoshida, T. M.; Nolan, J. P.; Jett, J. H.; Marrone, B. L. Probing the kinetics of SYTOX Orange stain binding to double-stranded DNA with implications for DNA analysis, Anal. Chem., 2005, 77, 3554-3562.

19. Yan, XM*; Tang, AJ; Schielke, E.G.; Hang, W; Nolan, J. P. On the development of a microsphere-based multiplexed immunoassay for influenza virus typing and subtyping by flow cytometry, Options for the control of influenza V, International Congress Series, 2004, 1263, 342-345.

18. Yan, XM*; Schielke, E.G.; Grace, K.M.; Hassell, C.; Marrone, B. L.; Nolan, J. P.* Microsphere-based duplexed immunoassay for influenza virus typing by flow cytometry, J. Immunol. Methods, 2004, 284, 27-38. 

17. Ferris, M. M.; Yan, XM; Habbersett, R. C.; Shou, YL; Lemanski, C. L.; Jett, J. H.; Yoshida, T. M.; Marrone, B. L. Performance assessment of DNA fragment sizing by high sensitivity flow cytometry and pulsed field gel electrophoresis, J. Clin. Microbiol., 2004, 42, 1965-1976.

16. Nolan, JP*; Habbersett, RC; Deshpande, A; Yan, XM; Bell, CS; Marrone, BL. Analysis of sub-micron biological particles by high sensitivity flow cytometry, Cytometry 2004, 59A, 52-53.

15. Yan, XM; Hang, W; Majidi, V.; Marrone, B. L.; Yoshida, T. M. Evaluation of different nucleic acid stains for sensitive dsDNA analysis with capillary electrophoresis separation, J. Chromatogr. A., 2002, 943, 275-285.  

14. Yan, XM; Ingeneri, K.; Hang, W; Harrison, W. W. Factors influencing signal profiles in microsecond pulsed glow discharge atomic emission spectrometry, J. Anal. At. Spectrom., 2001, 16, 819-824.

13. Yan, XM; Habbersett, R. C.; Cordek, J. M.; Nolan, J. P.; Yoshida, T. M.; Jett, J. H.; Marrone, B. L. Development of a mechanism-based, DNA staining protocol using SYTOX Orange nucleic acid stain and DNA fragment sizing flow cytometry, Anal. Biochem., 2000, 286, 138-148.

12. Yan, XM; Grace, W. K.; Yoshida, T. M.; Habbersett, R. C.; Velapan, N.; Jett, J. H.; Keller, R. A.; Marrone, B. L. Characteristics of different nucleic acid staining dyes for DNA fragment sizing by flow cytometry, Anal. Chem., 1999, 71, 5470-5480. 

11. Hang, W; Yan, XM; Wayne, D. M.*; Olivares, J. A.; Harrison, W. W.; Majidi, V. Glow discharge source interfacing to mass analyzers: Theoretical and practical considerations, Anal. Chem., 1999, 71, 3231-3237.

10. Hang, W; Yan, XM; Wayne, D. M.; Olivares, J. A.; Harrison, W. W.; Majidi, V.* Selective removal of matrix ion peaks in plasma source time-of-flight mass spectrometry: ion deflection and detector gating, J. Anal. At. Spectrom., 1999, 14, 1523-1526.

9. Duan, YX; Danen, R. E.; Yan, XM; Steiner, R.; Cuadrado, J.; Wayne, D.; Majidi, V.; Olivares, J. A*. Characterization of an improved thermal ionization cavity source for mass spectrometry, J. Am. Soc. Mass Spectrom., 1999, 10, 1008-1015.

8. Yan, XM; Hang, W; Smith, B. W.; Winefordner, J. D.; Harrison, W. W.* Primary studied of microsecond pulsed glow discharge as an emission sources by using conventional hollow cathode lamp, J. Anal. At. Spectrom., 1998, 13, 1033-1038.

7. Harrison, W. W.*; Hang, W; Yan, XM; Ingeneri, K.; Schilling, C. Temporal considerations with a pulsed glow discharge”, J. Anal. At. Spectrom., 1997, 12, 891-896.

6. Yan, XM*; Huang, BL; Tanaka, T.; Kawaguchi, H. Langmuir probe potential measurements for reduced pressure inductively coupled plasma mass spectrometry, J. Anal. At. Spectrom., 1997, 12, 697-701.

5. Yan, XM; Tanaka, T.; Kawaguchi, H.* Electrothermal vaporization for the determination of halogens by reduced pressure inductively coupled plasma mass spectrometry, Spectrochim. Acta B, 1996, 51, 1345-1353.

4. Yan, XM; Tanaka, T.; Kawaguchi, H.* Reduced pressure inductively coupled plasma mass spectrometry for nonmetallic elements, Appl. Spectrosc., 1996, 50, 182-187.

3. Wang, XR*; Zhuang, ZX; Yang, CL; Yang, PY; Yan, XM; Lin, JM. Development of transient data acquisition system for hyphenated techniques coupled with inductively coupled plasma atomic emission spectrometry, Spectrochim. Acta B, 1996, 51, 1753-1759.

2. Yan, XM; Wang, XR; Yang, PY; Hang, W; Huang, BL*. Signal Acquisition and processing in transient introduction techniques on-line hyphenated with multichannel ICP-AES, Chem. J. Chinese U., 1993, 14, 1506-1509.

1. Wang, XR*; Zhu, EY; Yan, XM; Yang, PY; Huang, BL; Zhuang, ZX. Chemometrics study on preliminary clinical diagnostics for cancer patients, Acta Chim. Sinica, 1993, 51, 1094-1098.